Article

Sex-specific microglial responses to glucocerebrosidase inhibition: relevance to GBA1-linked Parkinson disease

2022-12-05

Abstract excerpt

Microglia are heterogenous cells characterized by distinct populations each contributing to specific biological processes in the nervous system, including neuroprotection. To elucidate the impact of sex-specific microglia heterogenicity to the susceptibility of neuronal stress, we analysed the dynamic changes in shape and motility occurring in primary mouse microglia following pro-inflammatory or neurotoxic insult...

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Literature Corpus work: ab52bbf9-607e-5602-90c4-2f6e44354472
DOI: 10.1101/2022.12.05.519143

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