Article
Genetic determinants of cardiometabolic and pulmonary phenotypes and obstructive sleep apnoea in HCHS/SOL.
EBioMedicine - 1 Oct 2022
Zhang Yuan, Elgart Michael, Kurniansyah Nuzulul, Spitzer Brian W, Wang Heming, Kim Doyoon, Shah Neomi, Daviglus Martha, Zee Phyllis C, Cai Jianwen, Gottlieb Daniel J, Cade Brian E, Redline Susan, Sofer Tamar
Abstract excerpt
BACKGROUND: Obstructive Sleep Apnoea (OSA) often co-occurs with cardiometabolic and pulmonary diseases. This study is to apply genetic analysis methods to explain the associations between OSA and related phenotypes. METHODS: In the Hispanic Community Healthy Study/Study of Latinos, we estimated genetic correlations ρg between the respiratory event index (REI) and 54 anthropometric, glycemic, cardiometabolic, and...
Topics
- Blood Glucose
- Body Mass Index
- Cardiovascular Diseases
- Genome-Wide Association Study
- Glycated Hemoglobin
- Humans
- Insulin
- Phenotype
- Sleep Apnea, Obstructive