Article

COMPREHENSIVE GENETIC INVESTIGATION REVEALS HETEROGENEOUS PATHWAYS TO OBSTRUCTIVE SLEEP APNEA

2026-01-11

Abstract excerpt

<h4>ABSTRACT</h4> Obstructive sleep apnea (OSA) is a common, heritable disorder with diverse clinical presentations and etiologies. We conducted a genome-wide association meta-analysis of 492,107 individuals, including 46,028 OSA cases, identifying 14 genome-wide significant loci, eight of which are novel. Analyses adjusting for body mass index (BMI) revealed three loci independent of obesity, implicating alterna...

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Literature Corpus work: 5a40d9f7-b44d-58fe-840d-986cccc8e154
DOI: 10.64898/2026.01.08.26343696

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