Article

Cancer Spectrum in Mexican Patients with the CHEK2 p.(Leu236Pro) Variant: A Retrospective Study

2025-05-16

Abstract excerpt

<title>Abstract</title> <p>This study aimed to characterize the cancer spectrum associated with the most frequent pathogenic CHEK2 p.(Leu236Pro) variant for the first time in Mexican individuals. Despite its frequent detection in multi-gene panel testing, limited data on its associated cancer risks complicate genetic counseling and surveillance strategies. We retrospectively analyzed 5,759 patients with a multi-g...

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Literature Corpus work: 7f7502e6-2a45-5e7f-8952-7ade0699f7d0
DOI: 10.21203/rs.3.rs-6406420/v1

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