Article
Landscape of Multilocus Inherited Neoplasia Allele Syndrome in Mexican Population.
JCO global oncology - 1 Jan 2025
Aguilar Dione, Garza-Rodríguez María L, Pérez-Ibave Diana C, Muñiz-Garza Carolina E, Treviño Victor, Villarreal-Garza Cynthia M, Vidal-Gutiérrez Oscar, Burciaga-Flores Carlos H
Abstract excerpt
PURPOSE: Hereditary cancer syndromes (HCS) explain 5%-10% of all cancer cases. Patients with more than one germline pathogenic variant (GPV) result in a clinical syndrome known as multilocus inherited neoplasia allele syndrome (MINAS). In recent years, an increasing number of MINAS cases have been reported. This study aims to identify the prevalence of MINAS and determine the effect of two GPVs in HCS on patients...
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