Article

Temporal Ablation of the Ciliary Protein IFT88 Alters Normal Brainwave Patterns

2024-04-03

Abstract excerpt

The primary cilium is a hair-like organelle that hosts molecular machinery for various developmental and homeostatic signaling pathways. Its alteration can cause rare ciliopathies such as the Bardet-Biedl and Joubert syndromes, but is also linked to Alzheimer’s disease, clinical depression, and autism spectrum disorder. These afflictions are caused by disturbances in a wide variety of genes but a common phenotype...

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Literature Corpus work: 7f708e32-0612-58e2-974b-c6244ed41a8b
DOI: 10.1101/2024.04.03.587983

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