Article

Sleep slow-wave oscillations trigger seizures in a genetic epilepsy model of Dravet syndrome

2022-01-05

Abstract excerpt

Sleep is the brain state when cortical activity decreases and memory consolidates. However, in human epileptic patients, including genetic epileptic seizures such as Dravet syndrome, sleep is the preferential period when epileptic spike-wave discharges (SWDs) appear, with more severe epileptic symptoms in female patients than male patients, which influencing patient sleep quality and memory. Currently, seizure ons...

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Identifiers and source

Literature Corpus work: 729335ff-d883-520d-90ca-733e47ca0a7b
DOI: 10.1101/2022.01.04.474940

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