Article

A mouse model of Bardet-Biedl Syndrome has impaired fear memory, which is rescued by lithium treatment

2020-10-07

Abstract excerpt

Primary cilia are microtubule-based organelles present on most cells that regulate many physiological processes, ranging from maintaining energy homeostasis to renal function. However, the role of these structures in the regulation of behavior remains unknown. To study the role of cilia in behavior, we employ mouse models of the human ciliopathy, Bardet-Biedl Syndrome (BBS). Here, we demonstrate that BBS mice have...

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Literature Corpus work: 3ec82a01-c08b-5f56-8181-ea2aa5a9615a
DOI: 10.1101/2020.10.06.322883

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