Article

The evolution of an RNA-based memory of self in the face of genomic conflict

2022-06-20

Abstract excerpt

Distinguishing endogenous genes from selfish ones is essential for germline integrity. In animals, small regulatory RNAs play a central role in this process; however, the underlying principles are largely unknown. To fill this gap, we studied how selfish toxin-antidote elements (TAs) evade silencing in the nematode Caenorhabditis tropicalis . We found that the slow-1/grow-1 TA is active only when maternally inhe...

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Literature Corpus work: 7f6ce23b-62e6-5938-b2b1-7c619b9773fa
DOI: 10.1101/2022.06.17.496645

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