Article
Resolving tumor heterogeneity: genes involved in chordoma cell development identified by low-template analysis of morphologically distinct cells.
PloS one - 1 Jan 2014
El-Heliebi Amin, Kroneis Thomas, Wagner Karin, Meditz Katharina, Kolb Dagmar, Feichtinger Julia, Thallinger Gerhard G, Quehenberger Franz, Liegl-Atzwanger Bernadette, Rinner Beate
Abstract excerpt
The classical sacrococcygeal chordoma tumor presents with a typical morphology of lobulated myxoid tumor tissue with cords, strands and nests of tumor cells. The population of cells consists of small non-vacuolated cells, intermediate cells with a wide range of vacuolization and large heavily vacuolated (physaliferous) cells. To date analysis was only performed on bulk tumor mass because of its rare incidence,...
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