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Article

Mammalian pumilio proteins control cellular morphology, migration, and adhesion.

Scientific reports - 21 Feb 2023

Sternburg Erin L, Lillibridge Jordan J, Phandthong Rattapol, Karginov Fedor V

Abstract excerpt

Pumilio proteins are RNA-binding proteins that control mRNA translation and stability by binding to the 3' UTR of target mRNAs. Mammals have two canonical Pumilio proteins, PUM1 and PUM2, which are known to act in many biological processes, including embryonic development, neurogenesis, cell cycle regulation and genomic stability. Here, we characterized a new role of both PUM1 and PUM2 in regulating cell...

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Identifiers

PMID: 36810759
DOI: 10.1038/s41598-023-30004-4
PMCID: PMC9944931

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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