Article

Transcriptomic Changes During Stage Progression of Mycosis Fungoides

2021-04-21

Abstract excerpt

<h4>Background</h4> Mycosis fungoides (MF) is the most common cutaneous T cell lymphoma, which in the early patch/plaque stages runs an indolent course. However, ~25% of MF patients develop skin tumors, a hallmark of progression to the advanced stage and associated with high mortality. The mechanisms involved in stage progression are poorly elucidated. <h4>Methods</h4> We performed whole-transcriptome and whole-...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 7f122dbe-e4ba-5708-aae0-3f3d17d85f92
DOI: 10.1101/2021.04.20.440708

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Transcriptomic Changes During Stage Progression of Mycosis FungoidesDOI 10.1101/2021.04.20.440708Read

Transcriptomic changes during stage progression of mycosis fungoidesSemantic proximity Read

Single-cell RNA sequencing identifies subtypes of cancer-associated fibroblasts in early and late stages of mycosis fungoidesSemantic proximity Read

The mycosis fungoides cutaneous microenvironment shapes dysfunctional cell trafficking, antitumor immunity, matrix interactions, and angiogenesisSemantic proximity Read

Genomic profiling of mycosis fungoides identifies patients at high risk of disease progression.Semantic proximity Read

Whole-genome sequencing reveals oncogenic mutations in mycosis fungoides.Semantic proximity Read

Single-cell RNA sequencing reveals markers of disease progression in primary cutaneous T-cell lymphoma.Semantic proximity Read

Cutaneous T cell lymphoma atlas reveals malignant Th2 cells supported by a B cell-rich microenvironmentSemantic proximity Read

Branched evolution and genomic intratumor heterogeneity in the pathogenesis of cutaneous T-cell lymphomaSemantic proximity Read

Branched evolution and genomic intratumor heterogeneity in the pathogenesis of cutaneous T-cell lymphomaSemantic proximity Read

Single-cell RNA sequencing comparison of CD4+, CD8+ and T-cell receptor γδ+ cutaneous T-cell lymphomas reveals subset-specific molecular phenotypes.Semantic proximity Read

Mycosis Fungoides Is a Proliferation of Multiple Mutational Subclones.Semantic proximity Read

Integrative Mutational Landscape of Mycosis Fungoides Using a National Genomics RepositorySemantic proximity Read