Article

Single-cell RNA sequencing identifies subtypes of cancer-associated fibroblasts in early and late stages of mycosis fungoides

2025-09-10

Abstract excerpt

Mycosis fungoides (MF), the most common cutaneous T-cell lymphoma, is characterized by infiltration of malignant T-cells into the skin. While early-stage disease (IA-IIA) follows an indolent course, approximately 25% of patients progress to late-stage disease (IIB-IVB) with significantly worse prognosis and a median survival of 1-5 years. Identifying which early-stage MF patients are at high risk for disease progr...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 2bc3b297-1e8b-5f90-8f28-76b31fc4a37c
DOI: 10.1101/2025.09.07.25335167

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Single-cell RNA sequencing identifies subtypes of cancer-associated fibroblasts in early and late stages of mycosis fungoidesDOI 10.1101/2025.09.07.25335167Read

The mycosis fungoides cutaneous microenvironment shapes dysfunctional cell trafficking, antitumor immunity, matrix interactions, and angiogenesisSemantic proximity Read

Cutaneous T cell lymphoma atlas reveals malignant Th2 cells supported by a B cell-rich microenvironmentSemantic proximity Read

Transcriptomic Changes During Stage Progression of Mycosis FungoidesSemantic proximity Read

Single-cell RNA sequencing reveals markers of disease progression in primary cutaneous T-cell lymphoma.Semantic proximity Read

Transcriptomic changes during stage progression of mycosis fungoidesSemantic proximity Read

Single-cell RNA sequencing comparison of CD4+, CD8+ and T-cell receptor γδ+ cutaneous T-cell lymphomas reveals subset-specific molecular phenotypes.Semantic proximity Read

Single-cell RNA and T-cell receptor sequencing unveil mycosis fungoides heterogeneity and a possible gene signatureSemantic proximity Read

Multiomic Data Integration Reveals Microbial Drivers of Aetiopathogenesis in Mycosis FungoidesSemantic proximity Read

LCK and HOMER1 gene expression-based classifier distinguishes early mycosis fungoides from eczema and psoriasisSemantic proximity Read

Integrated genomic analyses of cutaneous T-cell lymphomas reveal the molecular bases for disease heterogeneity.Semantic proximity Read

The neoantigen landscape of mycosis fungoidesSemantic proximity Read

Unravelling the landscape of skin cancer through single-cell transcriptomicsSemantic proximity Read