Mycosis Fungoides Is a Proliferation of Multiple Mutational Subclones.

doi:10.1111/1346-8138.70159

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Article

Mycosis Fungoides Is a Proliferation of Multiple Mutational Subclones.

The Journal of dermatology - 1 Apr 2026

Honda Ryoma, Hamada Toshihisa, Sugaya Makoto

Abstract excerpt

Mycosis fungoides (MF) is a unique type of lymphoma with an excellent prognosis presenting with a wide variety of clinical and histological findings. Recent sophisticated research techniques have revealed that very slow changes in the clinical and histological pictures of one patient over time are due to intratumoral heterogeneity. This means the distribution of different subclones into individual skin lesions...

Topics

Humans
Mycosis Fungoides
Skin Neoplasms
Mutation
Skin
T-Lymphocytes
Cell Transformation, Neoplastic
Lymphoma, T-Cell, Cutaneous
Cell Proliferation

Source

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Identifiers

PMID: 41589349
DOI: 10.1111/1346-8138.70159
PMCID: PMC13075531

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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