Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Single-cell RNA sequencing reveals markers of disease progression in primary cutaneous T-cell lymphoma.

Molecular cancer - 28 Sept 2021

Rindler Katharina, Jonak Constanze, Alkon Natalia, Thaler Felix M, Kurz Harald, Shaw Lisa E, Stingl Georg, Weninger Wolfgang, Halbritter Florian, Bauer Wolfgang M, Farlik Matthias, Brunner Patrick M

Abstract excerpt

BACKGROUND: In early-stage mycosis fungoides (MF), the most common primary cutaneous T-cell lymphoma, limited skin involvement with patches and plaques is associated with a favorable prognosis. Nevertheless, approximately 20-30% of cases progress to tumors or erythroderma, resulting in poor outcome. At present, factors contributing to this switch from indolent to aggressive disease are only insufficiently...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biopsy
Share to Computational Biology

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Disease Progression

Share to Lymphoma, T-Cell, Cutaneous

Share to Mycosis Fungoides

Share to RNA-Seq

Share to Sequence Analysis, RNA

Share to Single-Cell Analysis

Source

Open in PubMed Open full text

Identifiers

PMID: 34583709
DOI: 10.1186/s12943-021-01419-2
PMCID: PMC8477535

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Single-cell RNA sequencing reveals markers of disease progression in primary cutaneous T-cell lymphoma.PMID 34583709Read ↗

Single-cell RNA sequencing identifies subtypes of cancer-associated fibroblasts in early and late stages of mycosis fungoidesSemantic proximity Read ↗

Single-cell RNA sequencing comparison of CD4+, CD8+ and T-cell receptor γδ+ cutaneous T-cell lymphomas reveals subset-specific molecular phenotypes.Semantic proximity Read ↗

Single-cell sequencing delineates T-cell clonality and pathogenesis of the parapsoriasis disease groupSemantic proximity Read ↗

Transcriptomic Changes During Stage Progression of Mycosis FungoidesSemantic proximity Read ↗

Single-cell RNA and T-cell receptor sequencing unveil mycosis fungoides heterogeneity and a possible gene signatureSemantic proximity Read ↗

Transcriptomic changes during stage progression of mycosis fungoidesSemantic proximity Read ↗

Genomic profiling of mycosis fungoides identifies patients at high risk of disease progression.Semantic proximity Read ↗

Cutaneous T cell lymphoma atlas reveals malignant Th2 cells supported by a B cell-rich microenvironmentSemantic proximity Read ↗

LCK and HOMER1 gene expression-based classifier distinguishes early mycosis fungoides from eczema and psoriasisSemantic proximity Read ↗

Integrated genomic analyses of cutaneous T-cell lymphomas reveal the molecular bases for disease heterogeneity.Semantic proximity Read ↗

Single-cell transcriptomics links malignant T cells to the tumor immune landscape in cutaneous T cell lymphomaSemantic proximity Read ↗

Skin colonization by circulating neoplastic clones in cutaneous T-cell lymphomaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.