Article
<p class="MDPI13authornames" style="margin-bottom: 12.0pt;">Pleiotropic Effects on Tachyzoite and Host Cell Proteomes in Knock-Out Clones of the Open Reading Frames 297720 and 319730 Constitutively Expressed in <em>T. gondii</em> ShSp1 Tachyzoites
2025-10-06
Abstract excerpt
Toxoplasma gondii, the causative agent of toxoplasmosis widespread in animals and humans, is an intracellular apicomplexan protozoan parasite infecting a variety of host cells. Gene editing using CRISPR-Cas9 has become a standard tool to investigate the molecular genetics of this interaction. With respect to gene knock-out (KO) studies, the general paradigm implies that the gene of interest is expressed in the wil...
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Identifiers and source
- Literature Corpus work
- 7eb3fb3d-40ae-57f0-a76c-825865ecf2d0
- DOI
- 10.20944/preprints202510.0212.v1
