Article
Evaluation of the basic functions of six calcium-dependent protein kinases in Toxoplasma gondii using CRISPR-Cas9 system.
Parasitology research - 1 Feb 2016
Wang Jin-Lei, Huang Si-Yang, Li Ting-Ting, Chen Kai, Ning Hong-Rui, Zhu Xing-Quan
Abstract excerpt
Toxoplasma gondii, an important protozoan parasite, infects almost all warm-blooded animals and humans. Although treatments in T. gondii are limited by the lack of effective drugs, some calcium-dependent kinases were demonstrated as the promising drug targets to chemotherapy against T. gondii due to their essential roles in T. gondii and absence from their hosts. The objectives of the present study were to...
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