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Single-cell RNA sequencing and spatial transcriptome analysis in bladder cancer: Current status and future perspectives

1 Jan 2025

Abstract excerpt

Background: Bladder cancer is one of the most prevalent malignancies, and the mechanisms underlying its progression and the role of the tumor microenvironment (TME) are unclear. Recent advancements in single-cell RNA sequencing (scRNA-seq) and spatial transcriptomics (ST) enable detailed analysis of the cellular heterogeneity, gene expression, and cell-cell interactions in bladder diseases. Methodology: We...

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PMID: 40034247
DOI: 10.1177/23523735251322017

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