Article
Urinary Molecular Pathology for Patients with Newly Diagnosed Urothelial Bladder Cancer.
The Journal of urology - 1 Oct 2021
Zhang Ruiyun, Zang Jingyu, Xie Feng, Zhang Yue, Wang Yiqiu, Jing Ying, Zhang Yi, Chen Zhaoxiong, Shahatiaili Akezhouli, Cai Mei-Chun, Zhao Zhixin, Du Pan, Jia Shidong, Zhuang Guanglei, Chen Haige
Abstract excerpt
PURPOSE: Next-generation sequencing (NGS)-based profiling of both urinary tumor DNA (utDNA) and circulating tumor DNA (ctDNA) shows promise for noninvasive detection and surveillance of urothelial bladder cancer (UBC). However, the analytical performance of these assays remains undefined in the real-world setting. Here, we sought to evaluate the concordance between tumor DNA (tDNA) profiling and utDNA or ctDNA...
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