Article

The <i>Iroquois</i> ( <i>Iro/Irx</i> ) homeobox genes are conserved Hox targets involved in motor neuron development

2024-05-30

Abstract excerpt

The Iroquois (Iro/Irx) homeobox genes encode transcription factors with fundamental roles in animal development. Despite their link to various congenital conditions in humans, our understanding of Iro/Irx gene expression, function, and regulation remains incomplete. Here, we conducted a systematic expression analysis of all six mouse Irx genes in the embryonic spinal cord. We found five Irx genes ( Irx1, Irx2...

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Literature Corpus work: 7e55f295-8de9-54af-84b0-bbb461db785e
DOI: 10.1101/2024.05.30.596714

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