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Article

An ancient role for collier/Olf/Ebf (COE)-type transcription factors in axial motor neuron development

18 Jan 2019

Abstract excerpt

BACKGROUND: Mammalian motor circuits display remarkable cellular diversity with hundreds of motor neuron (MN) subtypes innervating hundreds of different muscles. Extensive research on limb muscle-innervating MNs has begun to elucidate the genetic programs that control animal locomotion. In striking contrast, the molecular mechanisms underlying the development of axial muscle-innervating MNs, which control...

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PMID: 30658714
DOI: 10.1186/s13064-018-0125-6

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