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Article

Irx1 regulates dental outer enamel epithelial and lung alveolar type II epithelial differentiation.

Developmental biology - 1 Sept 2017

Yu Wenjie, Li Xiao, Eliason Steven, Romero-Bustillos Miguel, Ries Ryan J, Cao Huojun, Amendt Brad A

Abstract excerpt

The Iroquois genes (Irx) appear to regulate fundamental processes that lead to cell proliferation, differentiation, and maturation during development. In this report, the Iroquois homeobox 1 (Irx1) transcription factor was functionally disrupted using a LacZ insert and LacZ expression demonstrated stage-specific expression during embryogenesis. Irx1 is highly expressed in the brain, lung, digits, kidney, testis...

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Share to Alveolar Epithelial Cells
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28746823
DOI: 10.1016/j.ydbio.2017.07.011
PMCID: PMC5599132

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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