Article

Establishment of Novel Mouse Model of Dietary NASH Rapidly Progressing Into Liver Cirrhosis and Tumors

2023-05-02

Abstract excerpt

Non-alcoholic steatohepatitis (NASH), which is the most severe manifestation of non-alcoholic fatty liver disease (NAFLD), has been recognized as a major hepatocellular carcinoma (HCC) catalyst. However, the molecular mechanism of NAFLD-NASH-HCC sequence remains unclear and a specific and effective treatment for NASH has not yet been established. The progress in this field depends on the availability of reliable p...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 7e4a7604-6b59-5d17-a2fd-45d22128214b
DOI: 10.20944/preprints202305.0075.v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Establishment of Novel Mouse Model of Dietary NASH Rapidly Progressing Into Liver Cirrhosis and TumorsDOI 10.20944/preprints202305.0075.v1Read

Utilization of animal models to investigate nonalcoholic steatohepatitis-associated hepatocellular carcinoma.Semantic proximity Read

Longitudinal analysis of a dietary mouse model of non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH)Semantic proximity Read

Animal models of non-alcoholic fatty liver disease: current perspectives and recent advances.Semantic proximity Read

Differences in metabolic and liver pathobiology induced by two dietary mouse models of nonalcoholic fatty liver diseaseSemantic proximity Read

Hepatocellular carcinoma in the context of non-alcoholic steatohepatitis (NASH): recent advances in the pathogenic mechanisms.Semantic proximity Read

Genetically modified mouse models for the study of nonalcoholic fatty liver diseaseSemantic proximity Read

Molecular Pathogenesis of Nonalcoholic Steatohepatitis- (NASH-) Related Hepatocellular CarcinomaSemantic proximity Read

Mouse models in non‐alcoholic fatty liver disease and steatohepatitis researchSemantic proximity Read

Phenotypic and Metabolomic Characteristics of Mouse Models of Diet-Induced Hepatic SteatosisSemantic proximity Read

The expanding role of fish models in understanding non-alcoholic fatty liver diseaseSemantic proximity Read

Establishment of animal models for NASH and utilization for mining associated gut microbiotaSemantic proximity Read

One Week of CDAHFD Induces Steatohepatitis and Mitochondrial Dysfunction with Oxidative Stress in Liver.Semantic proximity Read