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Apoptotic vesicles rescue impaired mesenchymal stem cells and their therapeutic capacity for osteoporosis by restoring miR-145a-5p deficiency

2024-06-04

Abstract excerpt

<title>Abstract</title> <p>Apoptotic vesicles (apoVs) play a vital role in various pathological conditions; however, we have yet to fully understand their precise biological effects in rescuing impaired mesenchymal stem cells (MSCs) and regulating tissue homeostasis. Here, we proved that systemic infusion of bone marrow MSCs derived from wild-type (WT) mice effectively improved the osteopenia phenotype and hyperi...

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Literature Corpus work
7e479ec0-bc55-56b2-b471-080633f600c7
DOI
10.21203/rs.3.rs-4416138/v1
Open publication

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Apoptotic vesicles rescue impaired mesenchymal stem cells and their therapeutic capacity for osteoporosis by restoring miR-145a-5p deficiencyDOI 10.21203/rs.3.rs-4416138/v1
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