Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cell and Cell-Free Therapies to Counteract Human Premature and Physiological Aging: MSCs Come to Light

18 Oct 2021

Abstract excerpt

The progressive loss of the regenerative potential of tissues is one of the most obvious consequences of aging, driven by altered intercellular communication, cell senescence and niche-specific stem cell exhaustion, among other drivers. Mesenchymal tissues, such as bone, cartilage and fat, which originate from mesenchymal stem cell (MSC) differentiation, are especially affected by aging. Senescent MSCs show...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Extracellular vesicles in disease
Share to Mesenchymal stem cell research
Share to MicroRNA in disease regulation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 34683184
DOI: 10.3390/jpm11101043

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cell and Cell-Free Therapies to Counteract Human Premature and Physiological Aging: MSCs Come to LightPMID 34683184Read ↗

Aging and Mesenchymal Stem Cells: Basic Concepts, Challenges and StrategiesSemantic proximity Read ↗

Human ESC‐sEVs alleviate age‐related bone loss by rejuvenating senescent bone marrow‐derived mesenchymal stem cellsSemantic proximity Read ↗

Engineering Mesenchymal Stem Cells to Extend Healthspan: Therapeutic Potential, Challenges, and Future SolutionsSemantic proximity Read ↗

Mesenchymal Stem Cell Senescence and Rejuvenation: Current Status and ChallengesSemantic proximity Read ↗

Molecular Mechanisms Contributing to Mesenchymal Stromal Cell AgingSemantic proximity Read ↗

Mesenchymal Stem Cell Senescence during Aging:From Mechanisms to Rejuvenation StrategiesSemantic proximity Read ↗

Senescence in Mesenchymal Stem Cells: Functional Alterations, Molecular Mechanisms, and Rejuvenation StrategiesSemantic proximity Read ↗

Advances in mesenchymal stem cell and exosome-based therapies for aging and age-related diseasesSemantic proximity Read ↗

Stress-induced senescence in mesenchymal stem cells: Triggers, hallmarks, and current rejuvenation approachesSemantic proximity Read ↗

Rejuvenation of Mesenchymal Stem Cells to Ameliorate Skeletal AgingSemantic proximity Read ↗

Mesenchymal stem cell‐derived extracellular vesicles reduce senescence and extend health span in mouse models of agingSemantic proximity Read ↗

Immortalizing Mesenchymal Stromal Cells from Aged Donors While Keeping Their Essential FeaturesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.