Article

Adipocyte Extracellular Vesicles (Adevs) Promote a Proinflammatory and Profibrotic Profile in Human Renal and Endothelial Cells in Vitro

2025-02-10

Abstract excerpt

<title>Abstract</title> <p> In obesity,white adipose tissue (WAT) undergoes hypertrophic and hyperplastic changes that are driven by phenotypical changes in preadipocytes and adipocytes. WAT also causes a chronic inflammatory state that modifies gene expression and the secretome, including the shedding of adipose-derived extracellular vesicles (AdEVs) into the circulation, with these AdEVs affecting other cell t...

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Literature Corpus work: 33c174f6-e6f4-53eb-9fd3-3d056ad091f8
DOI: 10.21203/rs.3.rs-5942263/v1

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