Article

Extracellular vesicles produced by bone marrow mesenchymal stem cells attenuate renal fibrosis, in part by inhibiting the RhoA/ROCK pathway, in a UUO rat model

2020-05-12

Abstract excerpt

<title>Abstract</title> <p>Background: Renal interstitial fibrosis is a critical symptom of chronic kidney disease that is associated with high incidence. Extracellular vesicles produced by bone marrow mesenchymal stem cells (BMSC-EVs) can play important roles in the repair of injured tissues. Though numerous studies have reported the effect of EVs on renal fibrosis, the underlying mechanisms remain unclear. We h...

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Literature Corpus work: ebf1686e-463f-59a2-856d-931a9f73f7b7
DOI: 10.21203/rs.3.rs-17275/v2

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