Article

Inhibiting the reproduction of COVID-19-causing SARS-CoV-2 through perturbations in human cell metabolic network

2020-05-12

Abstract excerpt

Viruses, including the recent, COVID-19-causing SARS-CoV-2 rely on their host for re-production. Here, we made use of genomic and structural information from SARS-CoV-2 and related viruses to create a biomass function capturing the stoichiometric amino and nucleic acid requirements of SARS-CoV-2. By incorporating this function into a stoichiometric metabolic model of the human cell and applying metabolic flux bala...

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Literature Corpus work: 7e413fc4-e15d-5103-8c1a-e2aa02e3944a
DOI: 10.22541/au.158921754.46391270/v2

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