Article

Host metabolic reprogramming in response to SARS-Cov-2 infection

2020-08-05

Abstract excerpt

Understanding the pathogenesis of SARS-CoV-2 is important for developing effective treatment strategies. Viruses hijack the host metabolism to redirect the resources for their replication and survival. How SARS-CoV-2 influences the host metabolism is still unclear. In this study, we analyzed transcriptomic data obtained from different human respiratory cell lines and patient samples (Swab, PBMC, lung biopsy, BALF)...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 2045468a-c6e0-5611-b551-b28ccf19b4c0
DOI: 10.1101/2020.08.02.232645

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Host metabolic reprogramming in response to SARS-Cov-2 infectionDOI 10.1101/2020.08.02.232645Read

Genome-scale metabolic modeling reveals SARS-CoV-2-induced metabolic changes and antiviral targetsSemantic proximity Read

Genome‐scale metabolic modeling reveals SARS‐CoV‐2‐induced metabolic changes and antiviral targetsSemantic proximity Read

Genome Scale-Differential Flux Analysis reveals deregulation of lung cell metabolism on SARS Cov2 infectionSemantic proximity Read

Host metabolic reprogramming in response to SARS-CoV-2 infection: A systems biology approachSemantic proximity Read

Genome‐scale metabolic modelling of SARS‐CoV‐2 in cancer cells reveals an increased shift to glycolytic energy productionSemantic proximity Read

Conserved metabolic vulnerabilities across pathogenic coronaviruses nominate host-directed therapeutic targetsSemantic proximity Read

Metabolomics analysis reveals a potential role SARS-CoV-2 viral proteins in the regulation/perturbation of metabolic pathways associated with altered plasma metabolites in COVID-19 patientsSemantic proximity Read

Metabolic and mitochondria alterations induced by SARS-CoV-2 accessory proteins ORF3a, ORF9b, ORF9c and ORF10Semantic proximity Read

Inhibiting the reproduction of COVID-19-causing SARS-CoV-2 through perturbations in human cell metabolic networkSemantic proximity Read

SARS-CoV-2 infection rewires host cell metabolism and is potentially susceptible to mTORC1 inhibitionSemantic proximity Read

SARS-CoV-2 hijacks folate and one-carbon metabolism for viral replicationSemantic proximity Read

Predictive Systems Biology Modeling: Unraveling Host Metabolic Disruptions and Potential Drug Targets in Acute Viral InfectionsSemantic proximity Read