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Article

Dynamic metabolic modeling of ATP allocation during viral infection

2024-11-13

Abstract excerpt

<h4>Summary</h4> Viral pathogens, like SARS-CoV-2, hijack the host’s macromolecular production machinery, imposing an energetic burden that is distributed across cellular metabolism. To explore the dynamic metabolic tension between the host’s survival and viral replication, we developed a computational framework that uses genome-scale models to perform dynamic Flux Balance Analysis of human cell metabolism during...

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Literature Corpus work
0f5b20e9-de19-56a1-80b0-617f58ff3b55
DOI
10.1101/2024.11.12.623198
Open publication

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Dynamic metabolic modeling of ATP allocation during viral infectionDOI 10.1101/2024.11.12.623198
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