Article
Comparative genomic analysis of Mycobacterium tuberculosis clinical isolates.
BMC genomics - 13 Jun 2014
Liu Fei, Hu Yongfei, Wang Qi, Li Hong Min, Gao George F, Liu Cui Hua, Zhu Baoli
Abstract excerpt
BACKGROUND: Due to excessive antibiotic use, drug-resistant Mycobacterium tuberculosis has become a serious public health threat and a major obstacle to disease control in many countries. To better understand the evolution of drug-resistant M. tuberculosis strains, we performed whole genome sequencing for 7 M. tuberculosis clinical isolates with different antibiotic resistance profiles and conducted comparative...
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