Article

Reflection confocal microscopy for quantitative assessment of airway surface liquid dysregulation and pharmacological rescue in cystic fibrosis under near-physiological conditions

2024-03-06

Abstract excerpt

<h4>ABSTRACT</h4> Proper regulation of airway surface liquid (ASL) is essential for effective mucociliary clearance (MCC) in healthy airways, and ASL depletion due to deficient cystic fibrosis transmembrane conductance regulator (CFTR)-mediated anion/fluid secretion plays an important role in the pathogenesis of mucociliary dysfunction and chronic muco-obstructive lung disease in patients with cystic fibrosis (CF...

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Literature Corpus work: 7e139d5f-6a6c-572e-b92b-56cd8ad93bd8
DOI: 10.1101/2024.03.05.583496

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