Article

Mucus clearance as a primary innate defense mechanism for mammalian airways

2002-03-01

Abstract excerpt

Innate defenses in the lung Microanatomy of the airway surfaceWith the advent of the capacity to fix airway surface liquid (ASL) in vivo, using the perfluorocarbon/osmium technique pioneered by Sims et al. ( 12), and the development of well-differentiated (WD) human airway epithelial cultures that exhibit mucus transport in vitro (13), it is now possible to investigate the microanatomy of mucus transport on airway...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 662fd229-c35b-55d7-938a-38e9d83b8cda
DOI: 10.1172/jci200215217

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Mucus clearance as a primary innate defense mechanism for mammalian airwaysDOI 10.1172/jci200215217Read

Mucus as a Treatable Trait in Chronic Airway Diseases.Semantic proximity Read

Structure-Function Relationships Of Mucociliary Clearance In Human AirwaysSemantic proximity Read

Airway mucosa: secretory cells, mucus and mucin genesSemantic proximity Read

Series Introduction: Intrinsic and innate defenses in the lung: intersection of pathways regulating lung morphogenesis, host defense, and repairSemantic proximity Read

Anti-Aspergillus Activities of the Respiratory Epithelium in Health and DiseaseSemantic proximity Read

Mucus Hyperconcentration as a Unifying Aspect of the Chronic Bronchitic PhenotypeSemantic proximity Read

The Continuous Mucosal Liquid Layer: A Unified Hypothesis for Airway-Digestive Immune Surveillance, Mucociliary Transport, and Disease SusceptibilitySemantic proximity Read

Structure and Function of the Cell Surface (Tethered) MucinsSemantic proximity Read

Mucus Hyperconcentration as a Unifying Aspect of the Chronic Bronchitic Phenotype.Semantic proximity Read

Live imaging of the airway epithelium reveals that mucociliary clearance modulates SARS-CoV-2 spreadSemantic proximity Read

Structure and Function Relationships of Mucociliary Clearance in Human and Rat AirwaysSemantic proximity Read

Do Airway Epithelium Air–Liquid Cultures Represent the In Vivo Airway Epithelium Transcriptome?Semantic proximity Read