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The Continuous Mucosal Liquid Layer: A Unified Hypothesis for Airway-Digestive Immune Surveillance, Mucociliary Transport, and Disease Susceptibility

2026-05-12

Abstract excerpt

<h4>Background: </h4> The mucosal surfaces from the anterior nares to the anal canal are lined by a continuous liquid layer studied extensively in regional isolation — as airway surface liquid in pulmonary physiology, gastric mucus in gastroenterology, and nasal mucus in rhinology — but never conceptualized as a unified physiological system. Framework: This paper proposes that this continuous mucosal liquid layer...

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Literature Corpus work
67a78ea8-b31f-59f0-9ead-3a4d627f91ec
DOI
10.20944/preprints202605.0727.v1
Open publication

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