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Thyroid Hormone Transporters MCT8 and OATP1C1 are Expressed in Projection Neurons and Interneurons of Basal Ganglia and Motor Thalamus in the Adult Human and Macaque Brain

2023-04-20

Abstract excerpt

Monocarboxylate transporter 8 (MCT8) and organic anion-transporting polypeptide 1C1 (OATP1C1) are thyroid hormones (TH) transmembrane transporters relevant for the availability of TH in neural cells, crucial for their proper development and function. Mutations in MCT8 or OATP1C1 result in severe disorders with dramatic movement disability related to alterations in basal ganglia motor circuits. Mapping the expressi...

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Literature Corpus work: 7ded310d-c64f-5711-a9cd-0dedce4b3816
DOI: 10.20944/preprints202304.0602.v1

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Thyroid Hormone Transporters MCT8 and OATP1C1 are Expressed in Projection Neurons and Interneurons of Basal Ganglia and Motor Thalamus in the Adult Human and Macaque BrainDOI 10.20944/preprints202304.0602.v1Read

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