Article

An advanced strategy for comprehensive profiling of ADP-ribosylation sites using mass spectrometry-based proteomics

2018-12-21

Abstract excerpt

<h4>ABSTRACT</h4> ADP-ribosylation is a widespread post-translational modification (PTM) with crucial functions in many cellular processes. Here, we describe an in-depth ADP-ribosylome using our Af1521-based proteomics methodology for comprehensive profiling of ADP-ribosylation sites, by systematically assessing complementary proteolytic digestions and precursor fragmentation through application of electron-trans...

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Literature Corpus work: 7dcafabc-5a08-5c2f-9a46-7fe0f7178f1a
DOI: 10.1101/501353

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