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ADP-ribosylation from molecular mechanisms to therapeutic implications

1 Oct 2023

Abstract excerpt

ADP-ribosylation is a ubiquitous modification of biomolecules, including proteins and nucleic acids, that regulates various cellular functions in all kingdoms of life. The recent emergence of new technologies to study ADP-ribosylation has reshaped our understanding of the molecular mechanisms that govern the establishment, removal, and recognition of this modification, as well as its impact on cellular and...

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PMID: 37832523
DOI: 10.1016/j.cell.2023.08.030

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