Article

SRF transcriptionally regulates the oligodendrocyte cytoskeleton during CNS myelination

2022-09-22

Abstract excerpt

<h4>ABSTRACT</h4> Myelination of neuronal axons is essential for nervous system development. Myelination requires dramatic cytoskeletal dynamics in oligodendrocytes, but how actin is regulated during myelination is poorly understood. We recently identified serum response factor (SRF)—a transcription factor known to regulate expression of actin and actin regulators in other cell types—as a critical driver of myeli...

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Literature Corpus work: 7d6fda65-fca0-5f3e-ad1d-ab633abe3fb8
DOI: 10.1101/2022.09.21.508765

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