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Scalable Hypothalamic Arcuate Neuron Differentiation from Human Pluripotent Stem Cells Suitable for Modeling Metabolic and Reproductive Disorders

2024-07-02

Abstract excerpt

The hypothalamus, composed of several nuclei, is essential for maintaining our body’s homeostasis. The arcuate nucleus (ARC), located in the mediobasal hypothalamus, contains neuronal populations with eminent roles in energy and glucose homeostasis as well as reproduction. These neuronal populations are of great interest for translational research. To fulfill this promise, we used a robotic cell culture platform t...

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Literature Corpus work
7d695b64-29f7-5f81-8371-e11eb74fe5d8
DOI
10.1101/2024.06.27.601062
Open publication

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Scalable Hypothalamic Arcuate Neuron Differentiation from Human Pluripotent Stem Cells Suitable for Modeling Metabolic and Reproductive DisordersDOI 10.1101/2024.06.27.601062
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