Article
Organoid-like Functional Adrenal Gland Cortex Derived From Human Pluripotent Stem Cells
2026-07-01
Abstract excerpt
The adrenal cortex is a critical for life endocrine system. It manages metabolic homeostasis, electrolyte balance, stress response, and sex development. This is accomplished through the release of various steroids from a dynamically changing landscape of concentric cellular zones/layers. Adrenocortical dysfunction is implicated in pathologies ranging from adrenal insufficiency to hypertension. The in-depth investi...
Topics
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- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Hormonal Regulation and Hypertension
- Pluripotent Stem Cells Research
- Renal and related cancers
- Reproductive Biology and Fertility
- Sexual Differentiation and Disorders
- Single-cell and spatial transcriptomics
- Sperm and Testicular Function
Identifiers and source
- Literature Corpus work
- f87e1932-44e9-5109-a55f-f8c51975820c
- DOI
- 10.64898/2026.06.30.735632
