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Article

Physiological Characterization and Transcriptomic Properties of GnRH Neurons Derived From Human Stem Cells

14 Jun 2021

Abstract excerpt

Gonadotropin-releasing hormone (GnRH) neurons in the hypothalamus play a key role in the regulation of reproductive function. In this study, we sought an efficient method for generating GnRH neurons from human embryonic and induced pluripotent stem cells (hESC and hiPSC, respectively). First, we found that exposure of primitive neuroepithelial cells, rather than neuroprogenitor cells, to fibroblast growth factor...

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Share to Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
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PMID: 34125902
DOI: 10.1210/endocr/bqab120

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