Article

Combined quantification of intracellular (phospho-)proteins and transcriptomics from fixed single cells

2018-06-27

Abstract excerpt

Environmental stimuli often lead to heterogeneous cellular responses and transcriptional output. We developed single-cell RNA and Immunodetection (RAID) to allow combined analysis the transcriptome and intracellular (phospho-)proteins from fixed single cells. RAID successfully recapitulated differentiation-state changes at the protein and mRNA level in human keratinocytes. Furthermore, we show that differentiated...

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Literature Corpus work: 7cfedf6c-2902-5380-9b82-63387c48953b
DOI: 10.1101/356329

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