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Multiplexed phosphoproteomics of low cell numbers using SPARCE

2024-10-19

Abstract excerpt

Understanding cellular diversity and disease mechanisms requires global analysis of proteins and their modifications. While next-generation sequencing has advanced our understanding of cellular heterogeneity, it fails to capture downstream signalling networks. Ultrasensitive mass spectrometry-based proteomics enables unbiased protein-level analysis of low cell numbers, down to single cells. However, phosphoproteom...

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Literature Corpus work
0c6ef1e1-89eb-5240-be52-964a55db3f1a
DOI
10.1101/2024.10.18.619068
Open publication

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Multiplexed phosphoproteomics of low cell numbers using SPARCEDOI 10.1101/2024.10.18.619068
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