Article
Immuno-detection by sequencing enables large-scale high-dimensional phenotyping in cells.
Nature communications - 19 Jun 2018
van Buggenum Jessie A G, Gerlach Jan P, Tanis Sabine E J, Hogeweg Mark, Jansen Pascal W T C, Middelwijk Jesse, van der Steen Ruud, Vermeulen Michiel, Stunnenberg Hendrik G, Albers Cornelis A, Mulder Klaas W
Abstract excerpt
Cell-based small molecule screening is an effective strategy leading to new medicines. Scientists in the pharmaceutical industry as well as in academia have made tremendous progress in developing both large-scale and smaller-scale screening assays. However, an accessible and universal technology for measuring large numbers of molecular and cellular phenotypes in many samples in parallel is not available. Here we...
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