Article

An organ-resolved rat FFPE phosphoproteome map enables directional kinase activity inference

2026-07-31

Abstract excerpt

Formalin-fixed paraffin-embedded (FFPE) tissue is the dominant clinical pathology resource yet whether it faithfully preserves organ signalling biology and supports directional regulatory analysis remains unquantified. We generated a phosphoproteome map from eight healthy rat organs, separating preservation effects from biological variation. Using mass spectrometry, we quantified 54,710 phosphosites on 5,994 prote...

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Literature Corpus work: bbd5df38-0cc6-522c-82b5-8ab756d86f81
DOI: 10.64898/2026.07.28.741173

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