Article

Small molecule oxybutynin rescues proliferative capacity of complex III-defective MPCs

2024-11-09

Abstract excerpt

<h4>ABSTRACT</h4> Mitochondrial disease encompasses a group of genetically inherited disorders hallmarked by an inability of the respiratory chain to produce sufficient ATP. These disorders present with multisystemic pathologies that predominantly impact highly energetic tissues such as skeletal muscle. There is no cure or effective treatment for mitochondrial disease. We have discovered a small molecule known as...

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Literature Corpus work: 7ce223f9-4ec5-523e-b4a9-fcd709501725
DOI: 10.1101/2024.11.08.622694

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Small molecule oxybutynin rescues proliferative capacity of complex III-defective MPCsDOI 10.1101/2024.11.08.622694Read

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