Article

Global identification of RsmA/N binding sites in <i>Pseudomonas aeruginosa</i> by <i>in vivo</i> UV CLIP-seq

2020-08-25

Abstract excerpt

<h4>ABSTRACT</h4> Posttranscriptional regulation of gene expression in bacteria is performed by a complex and hierarchical signaling cascade. Pseudomonas aeruginosa harbors two redundant RNA-binding proteins RsmA/RsmN (RsmA/N), which play a critical role in balancing acute and chronic infections. However, in vivo binding sites on target transcripts and the overall impact on the physiology remains unclear. In th...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 9dbfdb82-0759-5d5e-abcb-176a46d2616e
DOI: 10.1101/2020.08.24.265819

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Global identification of RsmA/N binding sites in <i>Pseudomonas aeruginosa</i> by <i>in vivo</i> UV CLIP-seqDOI 10.1101/2020.08.24.265819Read

Structural basis of sRNA RsmZ regulation of <i>Pseudomonas aeruginosa</i> virulenceSemantic proximity Read

A Grad-seq view of RNA and protein complexes in <i>Pseudomonas aeruginosa</i> under standard and bacteriophage predation conditionsSemantic proximity Read

Transcription inhibitors with XRE DNA-binding and cupin signal-sensing domains drive metabolic diversification in <i>Pseudomonas</i>Semantic proximity Read

Determination of the Two-Component Systems regulatory network reveals core and accessory regulations across <i>Pseudomonas aeruginosa</i> lineagesSemantic proximity Read

Critical functions and key interactions mediated by the RNase E scaffolding domain in <i>Pseudomonas aeruginosa</i>Semantic proximity Read

Integrative Transcriptomic and Network Analysis Reveals Small Open Reading Frames as Regulators of DNA Methylation-Linked Pathogenicity and Adaptability in <i>Leptospira interrogans</i>Semantic proximity Read

RtmR is a membrane-embedded RRM-family RNA-binding proteinSemantic proximity Read

Functional Analyses of the RsmY and RsmZ Small Noncoding Regulatory RNAs in Pseudomonas aeruginosa.Semantic proximity Read

SpxA1 and SpxA2 Function as a Stoichiometry-Dependent Regulatory Rheostat Governing Virulence Gene Expression in Group A StreptococcusSemantic proximity Read

Modeling binding of the conserved Csr/Rsm protein family across species of the γ-proteobacteria reveals niche-specific adaptation of the post-transcriptional regulonSemantic proximity Read

DNA uptake and twitching motility are controlled by the small RNA Arp through repression of pilin translation in <i>Acinetobacter baumannii</i>Semantic proximity Read

The RNA-binding protein RbpB is a central regulator of polysaccharide utilization in gut <i>Bacteroides</i>Semantic proximity Read