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Optimizing Amodiaquine Dosing in Nigeria: A Population Pharmacokinetic Study to Inform Seasonal Malaria Chemoprevention

2025-07-15

Abstract excerpt

<title>Abstract</title> <p>Amodiaquine-containing antimalarial combinations have been shown to be effective for both malaria treatment and seasonal malaria chemoprevention in children under five years of age, particularly in high-burden regions such as Nigeria. This study developed a population pharmacokinetic model to describe amodiaquine disposition and simulate desethylamodiaquine concentrations, providing ins...

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Literature Corpus work
7c8ddf75-f41c-5f31-8449-4179bfb0bb17
DOI
10.21203/rs.3.rs-6879693/v1
Open publication

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Optimizing Amodiaquine Dosing in Nigeria: A Population Pharmacokinetic Study to Inform Seasonal Malaria ChemopreventionDOI 10.21203/rs.3.rs-6879693/v1
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