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Pharmacometric evaluation of amodiaquine-sulfadoxine-pyrimethamine and dihydroartemisinin-piperaquine seasonal malaria chemoprevention in northern Uganda

2025-06-25

Abstract excerpt

<h4>Background</h4> Seasonal malaria chemoprevention (SMC) using monthly amodiaquine-sulfadoxine-pyrimethamine (SPAQ) is being deployed East Africa, where antimalarial drug resistance levels are high. Dihydroartemisinin-piperaquine (DP) is a potential alternative. <h4>Methods</h4> A 28 day pharmacometric assessment of SMC was conducted in Karamoja, Northern Uganda. In two villages children received SPAQ and in one...

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Literature Corpus work
3f563dac-61d5-54b0-8563-a1aff4eec055
DOI
10.1101/2025.06.24.25330200
Open publication

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