Alternative promoters drive human cytomegalovirus reactivation from latency

Abstract excerpt

Significance Cytomegalovirus is a herpesvirus that persists latently for the host’s lifetime, with periodic reactivation that can cause life threatening disease in individuals with inadequate immunity. Understanding the mechanisms by which the virus reactivates is critical to controlling reactivation and disease. For decades, reactivation of viral gene expression and replication has been presumed to be driven...

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